Cord Blood Banking

Umbilical Cord Blood Collection

 
Cord Blood found inside the umbilical cord of newborn babies is a rich source of stem cells, such as haematopoietic stem cells (HSCs). These cells are the building blocks in your baby’s blood and immune system. They can multiply and mature into other blood cells to regenerate and replenish our immune system.

Haematopoietic Stem Cells (HSCs) are found in cord blood, the bone marrow and peripheral blood. Its main characteristic is its ability to regenerate organ tissues, the blood and immune systems. It also differentiates into blood components such as red blood cells to bring oxygen around the body, white blood cells to fight infections, and platelets for healing.

Cord Blood is safer and easier to get because they are readily obtained from the placenta at the time of delivery. Harvesting stem cells from bone marrow require a surgical procedure, usually under general anesthesia, that can cause postoperative pain and poses a small risk to the donor.

Cord blood also is less likely to contain infectious agents, like some viruses, that can pose a risk to transplant recipients. In addition, cord blood may have a greater ability to generate new blood cells than bone marrow. Ounce for ounce, there are nearly 10 times as many blood-producing cells in cord blood. This fact suggests that a smaller number of cord blood stem cells are needed for a successful transplantation.
 

What is Cord Blood Banking?

Cord Blood Banking is the collection and preservation of blood stem cells taken from the umbilical cord after the baby is safely delivered — for use in the treatment of various diseases in the future. Cord blood is one of the richest sources of pluripotent adult stem cells. The only chance to collect these precious cells is at the time of the baby’s birth.

By choosing to save this precious source of cord blood stem cells, you safeguard the health of your child, and also that of your family. Moreover, with the ongoing worldwide research, you are actually preserving a precious lifeline that bear endless possibilities.

Currently, technology can program stem cells to turn into red blood cells, white blood cells, platelets, liver, kidney, brain, nerve cells, etc. and could be used to repair damaged tissues and restore diseased organs.

 

How is Cord Blood Collected and Stored?

Cord Blood Banking is the saving of this life-giving source of precious stem cells from the umbilical cord. An example is shown in the flowchart below:

1. SAFE AND PAINLESS COLLECTION
After delivering your baby, your doctor will clamp and cut the umbilical cord, and collect the cord blood with a sterile blood bag. This is a safe, painless and quick procedure for both the mother and baby.

2. PICK-UP AND TRANSPORTATION WITH 48 HOURS TO THE LABORATORY
Call StemCord’s 24-hour Hotline and we will send your baby’s cord blood to StemCord’s laboratory in Singapore for processing and storage under stringent conditions.

3. STRINGENT STANDARDS OF PROCESSING
Cord blood is processed using the SepaxⓇ2 fully automated, mobile and closed capability system for the efficient and consistent processing of cord blood.

4. LONG TERM STORAGE IN MULTIPLE CRYOBAGS
Processed cord blood is stored in multiple cryo bags and hermetically sealed, before being systematically frozen, minus 1 Degree Celsius at a time to preserve the integrity of each stem cell. When the temperature reaches -150 Degree Celcius or colder, the stem cells are cryopreserved in a vapour phase liquid nitrogen.

5. RETRIEVAL AND TRANSFER IN 72 HOURS’ FORMAL NOTICE
The frozen cord blood can be thawed and ready for immediate use when your family needs it..The cord blood will be released to you on 72 hours’ notice. For transplant purposes to a location within Singapore, StemCord will arrange for the delivery of the Cord Blood at no additional charge to the client.

 

Diseases Currently Treated with Stem Cells

Cord Blood Stem Cell Treatments

Today, thousands of cord blood stem cell transplants have taken place around the world to treat more than 70 diseases. The list continues to grow as research advances. These include:

 

Cancers

  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Burkitt’s Lymphoma
  • Chronic Myelogenous Leukemia (CML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Liposarcoma
  • Myelodysplastic Syndrome (MDS)
  • Chronic Myelomonocytic Leukemia (CMML)
  • Neuroblastoma
  • Non-Hodgkin’s Lymphoma
  • Hodgkin’s Lymphoma
  • Langerhans Cell Histiocytosis

 

Bone Marrow Failure Syndrome

  • Severe Aplastic Anemia
  • Diamond-Blackfan Anemia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Amegakaryocytic Thrombocytopenia
  • Kostmann’s Syndrome

 

Hemoglobinopathies Blood Disorders

  • Sickle-Cell Anemia
  • Thalassemia (Cooley’s Anemia)

 

Inborn Errors of Metabolism

  • Adrenoleukodystrophy
  • Batten Disease (Inherited Neuronal Ceroid Lipofuscinosis)
  • Gunther Disease
  • Hunter Syndrome
  • Hurler Syndrome
  • Krabbe Disease (Global Cell Leukodystrophy)
  • Lesch-Nyhan Disease
  • Maroteaux-Lamy Syndrome

 

Immunodeficiencies

  • Omenn’s Syndrome
  • Severe Combined Immunodeficiency (SCID or SCID – ADA)
  • Reticular Dysplasia
  • Thymic Dysplasia
  • Wiskott-Aldrich Syndrome
  • X-linked Lymphoproliferative Disease
  • Leukocyte-Adhesion Deficiency

 

Other Diseases

  • Evans Syndrome
  • Familial Hemophagocytic Lymphohistiocytosis
  • EBV-assoc. Hemophagocytic Lymphohistiocytosis
  • Osteopetrosis